Clínica Médica

Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial.

JAMA. 2026 Mar; 335(Mar):775-786. doi: 10.1001/jama.2025.24175. pii: .

Navigating Conflicting Vaccination Recommendations: Guidance for Clinicians.

JAMA. 2026 Mar; 335(Mar):847-849. doi: 10.1001/jama.2026.0276. pii: .

Positional dyspnea: A brief review.

The American journal of medicine. 2026 Mar; 139(Mar):287-298. doi: 10.1016/j.amjmed.2025.11.016. pii: S0002-9343(25)00819-8.

Update in Outpatient General Internal Medicine: Practice-Changing Evidence Published in 2025.

The American journal of medicine. 2026 Mar; doi: 10.1016/j.amjmed.2026.02.048. pii: S0002-9343(26)00149-X.

Management of Crohn Disease in Adults.

JAMA. 2026 Apr; doi: 10.1001/jama.2026.1239. pii: .

Pathophysiology of Gastroesophageal Reflux Disease.

Digestion. 2026 ; 107():185-201. doi: 10.1159/000547023. pii: .

ACG Clinical Guideline: Hepatic Encephalopathy.

The American journal of gastroenterology. 2026 Mar; 121(Mar):588-618. doi: 10.14309/ajg.0000000000003899. pii: .

Frailty: An overview.

Journal of family medicine and primary care. 2026 Jan; 15(Jan):39-44. doi: 10.4103/jfmpc.jfmpc_1748_25. pii: .

Guidelines and tools to assess appropriateness of diuretic prescribing and aid deprescribing: a systematic review.

The lancet. Healthy longevity. 2026 Mar; 7(Mar):100828. doi: 10.1016/j.lanhl.2026.100828. pii: S2666-7568(26)00012-7.

Acute cholangitis.

The British journal of surgery. 2026 Mar; 113(Mar):doi: 10.1093/bjs/znag010. pii: znag010.

Addressing Primary Care Needs in People Living With Sickle Cell Disease : A Narrative Review.

Annals of internal medicine. 2026 Mar; 179(Mar):394-401. doi: 10.7326/ANNALS-25-04647. pii: .

Chronic, Noninfectious Diarrhea: A Review.

JAMA. 2026 Apr; 335(Apr):1250-1262. doi: 10.1001/jama.2026.0872. pii: .

Functional Dyspepsia.

The New England journal of medicine. 2026 Apr; 394(Apr):1349. doi: 10.1056/NEJMc2601477. pii: 10.1056/NEJMc2601477#sa1.

Type 1 Diabetes: A Review.

JAMA. 2026 Mar; 335(Mar):1070-1083. doi: 10.1001/jama.2026.0048. pii: .

Case 9-2026: A 12-Year-Old Girl with Altered Mental Status and Hypoglycemia.

The New England journal of medicine. 2026 Mar; 394(Mar):1216-1225. doi: 10.1056/NEJMcpc2517859. pii: .

Hypertension: diagnosis, management, and new therapeutic targets.

European heart journal. 2026 Apr; 47(Apr):1633-1638. doi: 10.1093/eurheartj/ehag224. pii: .

A 9-Year-Old Girl with Persistent Fevers and Lethargy.

NEJM evidence. 2026 Apr; 5(Apr):EVIDmr2400406. doi: 10.1056/EVIDmr2400406. pii: .

Sepsis.

Lancet (London, England). 2026 Mar; 407(Mar):1276-1288. doi: 10.1016/S0140-6736(25)02422-5. pii: S0140-6736(25)02422-5.

State-of-the-Art Review: Chagas Disease-an Enduring Challenge.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Feb; 82(Feb):187-205. doi: 10.1093/cid/ciaf654. pii: .

Fatigue and Disease.

JAMA. 2026 Mar; 335(Mar):914. doi: 10.1001/jama.2025.15717. pii: .

Chronic kidney disease.

Lancet (London, England). 2026 Jan; 407(Jan):90-104. doi: 10.1016/S0140-6736(25)01942-7. pii: S0140-6736(25)01942-7.

Prostate cancer.

Lancet (London, England). 2026 Feb; 407(Feb):622-636. doi: 10.1016/S0140-6736(25)02221-4. pii: S0140-6736(25)02221-4.

A 44-Year-Old Man with Back Pain and Weakness.

NEJM evidence. 2026 Feb; 5(Feb):EVIDmr2500137. doi: 10.1056/EVIDmr2500137. pii: .

Cardiogenic Shock.

The New England journal of medicine. 2026 Jan; 394(Jan):62-77. doi: 10.1056/NEJMra2312086. pii: .

Consensus guidelines for ambulatory care for neutropenic fever.

Internal medicine journal. 2025 Dec; 55 Suppl 7(Dec):95-114. doi: 10.1111/imj.70251. pii: .

Consensus guidelines for antibacterial prophylaxis in patients with neutropenia.

Internal medicine journal. 2025 Dec; 55 Suppl 7(Dec):115-135. doi: 10.1111/imj.70250. pii: .

Consensus guidelines for the subsequent management of neutropenic fever after empiric therapy.

Internal medicine journal. 2025 Dec; 55 Suppl 7(Dec):68-94. doi: 10.1111/imj.70249. pii: .

Consensus guidelines for initial management of neutropenic fever.

Internal medicine journal. 2025 Dec; 55 Suppl 7(Dec):43-67. doi: 10.1111/imj.70248. pii: .

American Burn Association Clinical Practice Guidelines on Burn Shock Resuscitation.

Journal of burn care & research : official publication of the American Burn Association. 2024 May; 45(May):565-589. doi: 10.1093/jbcr/irad125. pii: .

Vaccination as a new form of cardiovascular prevention: a European Society of Cardiology clinical consensus statement.

European heart journal. 2025 Sep; 46(Sep):3518-3531. doi: 10.1093/eurheartj/ehaf384. pii: .

Diagnosis and Evaluation of Hypersensitivity Pneumonitis: CHEST Guideline and Expert Panel Report.

Chest. 2021 08; 160(08):e97-e156. doi: 10.1016/j.chest.2021.03.066. pii: S0012-3692(21)00686-3.

AGA Clinical Practice Update on Diagnosis and Management of Cyclic Vomiting Syndrome: Commentary.

Gastroenterology. 2024 Sep; 167(Sep):804-811.e1. doi: 10.1053/j.gastro.2024.05.031. pii: S0016-5085(24)05025-X.

Hyperglycemic crises in adults: A look at the 2024 consensus report.

Cleveland Clinic journal of medicine. 2025 Mar; 92(Mar):152-158. doi: 10.3949/ccjm.92a.24089. pii: .

EAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults.

Surgical endoscopy. 2024 Aug; 38(Aug):4104-4126. doi: 10.1007/s00464-024-10977-7. pii: .

Prevention of Episodic Migraine Headache Using Pharmacologic Treatments in Outpatient Settings: A Clinical Guideline From the American College of Physicians.

Annals of internal medicine. 2025 Feb; doi: 10.7326/ANNALS-24-01052. pii: .

2024 American Heart Association and American Red Cross Guidelines for First Aid.

Circulation. 2024 Dec; 150(Dec):e519-e579. doi: 10.1161/CIR.0000000000001281. pii: .

Meningitis (bacterial) and meningococcal disease: recognition, diagnosis and management-summary of updated NICE guidance.

BMJ (Clinical research ed.). 2024 Nov; 387(Nov):q2452. doi: 10.1136/bmj.q2452. pii: .

Acute respiratory distress syndrome.

BMJ (Clinical research ed.). 2024 Oct; 387(Oct):e076612. doi: 10.1136/bmj-2023-076612. pii: .

New horizons in clinical practice guidelines for use with older people.

Age and ageing. 2024 Jul; 53(Jul):doi: 10.1093/ageing/afae158. pii: afae158.

Anaphylaxis: A 2023 practice parameter update.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2024 Feb; 132(Feb):124-176. doi: 10.1016/j.anai.2023.09.015. pii: S1081-1206(23)01304-2.

The syncope core management process in the emergency department: a consensus statement of the EUSEM syncope group.

European journal of emergency medicine : official journal of the European Society for Emergency Medicine. 2024 Aug; 31(Aug):250-259. doi: 10.1097/MEJ.0000000000001146. pii: .

Protocol for the development and validation of a Polypharmacy Assessment Score.

Diagnostic and prognostic research. 2024 Jul; 8(Jul):10. doi: 10.1186/s41512-024-00171-7. pii: 10.

World Gastroenterology Organisation Global Guidelines: Probiotics and Prebiotics.

Journal of clinical gastroenterology. 2024 Jul; 58(Jul):533-553. doi: 10.1097/MCG.0000000000002002. pii: .

AGA Clinical Practice Update on Management of Iron Deficiency Anemia: Expert Review.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2024 Aug; 22(Aug):1575-1583. doi: 10.1016/j.cgh.2024.03.046. pii: S1542-3565(24)00410-5.

An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline.

American journal of respiratory and critical care medicine. 2024 Jan; 209(Jan):24-36. doi: 10.1164/rccm.202311-2011ST. pii: .

When Blood Pressure Increases with Standing: Consensus Definition for Diagnosing Orthostatic Hypertension.

Blood pressure. 2023 Dec; 32(Dec):2161871. doi: 10.1080/08037051.2022.2161871. pii: .

CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports. 2022 Nov; 71(Nov):1-95. doi: 10.15585/mmwr.rr7103a1. pii: .

Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.

American journal of respiratory and critical care medicine. 2022 05; 205(05):e18-e47. doi: 10.1164/rccm.202202-0399ST. pii: .

What Is Adrenal Insufficiency?

JAMA. 2026 Apr; 335(Apr):1280. doi: 10.1001/jama.2025.23130. pii: .

Chronic, Noninfectious Diarrhea: A Review.

JAMA. 2026 Apr; 335(Apr):1250-1262. doi: 10.1001/jama.2026.0872. pii: .

Management of Crohn Disease in Adults.

JAMA. 2026 Apr; doi: 10.1001/jama.2026.1239. pii: .

What Is Ovarian Cancer?

JAMA. 2026 Apr; 335(Apr):1188. doi: 10.1001/jama.2025.18446. pii: .

Insufficient Sleep Among US Adolescents Across Behavioral Risk Groups.

JAMA. 2026 Apr; 335(Apr):1173-1176. doi: 10.1001/jama.2026.1417. pii: e261417.

Hypertension: diagnosis, management, and new therapeutic targets.

European heart journal. 2026 Apr; 47(Apr):1633-1638. doi: 10.1093/eurheartj/ehag224. pii: .

Functional Dyspepsia.

The New England journal of medicine. 2026 Apr; 394(Apr):1349. doi: 10.1056/NEJMc2601477. pii: 10.1056/NEJMc2601477#sa1.

A 9-Year-Old Girl with Persistent Fevers and Lethargy.

NEJM evidence. 2026 Apr; 5(Apr):EVIDmr2400406. doi: 10.1056/EVIDmr2400406. pii: .

Sepsis.

Lancet (London, England). 2026 Mar; 407(Mar):1276-1288. doi: 10.1016/S0140-6736(25)02422-5. pii: S0140-6736(25)02422-5.

Case 9-2026: A 12-Year-Old Girl with Altered Mental Status and Hypoglycemia.

The New England journal of medicine. 2026 Mar; 394(Mar):1216-1225. doi: 10.1056/NEJMcpc2517859. pii: .